BDBM50093196 CHEMBL78283::Derivative of piperazine-1-carboxylic acid 5-(piperazine-1-carbonyloxymethyl)-tricyclo[3.3.1.1*3,7*]decan-1-ylmethyl ester

SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(-[#6]-[#7]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#8]-[#6]C23[#6]-[#6]-4-[#6]-[#6](-[#6]2)-[#6]C([#6]-[#8]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#7]-[#6]-c2ccc(cc2)\[#7]=[#6](/[#7])-[#7])([#6]-4)[#6]3)cc1

InChI Key InChIKey=ANCMGNKVWBLMLM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50093196   

TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093196(CHEMBL78283 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  10nMAssay Description:Evaluated for its inhibitory potency against tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093196(CHEMBL78283 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  1.70E+4nMAssay Description:Compound was evaluated for its inhibitory potency against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093196(CHEMBL78283 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  3.63E+5nMAssay Description:Compound was evaluated for its inhibitory potency against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093196(CHEMBL78283 | Derivative of piperazine-1-carboxyli...)
Affinity DataKi:  5.76E+5nMAssay Description:Compound was evaluated for its inhibitory potency against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed