BDBM50094683 1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea::1-(3-chlorophenyl)-3-(2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea::CHEMBL142562

SMILES Clc1cccc(NC(=O)Nc2nc3n[nH]cc3c3nc(nn23)-c2ccco2)c1

InChI Key InChIKey=CSGAYPUTEQNSDK-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50094683   

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094683(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 0.34-0.73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094683(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094683(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094683(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,...)
Affinity DataKi:  0.500nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094683(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,...)
Affinity DataKi:  70nMAssay Description:Tested for inhibitory activity against Adenosine A2b receptor by displacement of [3H]-DPCPX expressed in CHO cells ; value ranges from 61-80More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094683(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,...)
Affinity DataKi:  238nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells; range 179-317More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094683(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,...)
Affinity DataKi:  248nMAssay Description:Displacement of [3H]-SCH- 58261 from human adenosine A2A receptor expressed in CHO cells; range 218-283More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094683(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,...)
Affinity DataKi:  248nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094683(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,...)
Affinity DataKi:  501nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50094683(1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of cAMP accumulation in CHO cells expressing human A3 adenosine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed