BDBM50094699 1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-chloro-phenyl)-urea::1-(8-butyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-chlorophenyl)urea::CHEMBL423934

SMILES CCCCn1cc2c(n1)nc(NC(=O)Nc1cccc(Cl)c1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=OIVZKXGLPGFSTR-UHFFFAOYSA-N

Data  14 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50094699   

TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50094699(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]-MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 0.52-0.68More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50094699(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A2b receptor expressed in CHO cells; range 56-89More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50094699(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]-SCH- 58261 from human adenosine A2A receptor expressed in CHO cells; range 70-130More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50094699(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataKi:  245nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells; range 213-281More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50094699(1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]t...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of cAMP accumulation in CHO cells expressing human adenosine A3 receptor; range 3.0-6.9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed