BDBM50094708 CHEMBL3589347

SMILES COC(=O)CCCCCCC(=O)Nc1ccc(OS(=O)(=O)C2CC3OC2C(=C3c2ccc(O)cc2)c2ccc(O)cc2)cc1

InChI Key InChIKey=JFXBEKISTKFVAB-AJQTZOPKSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50094708   

TargetEstrogen receptor(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50094708(CHEMBL3589347)
Affinity DataKi:  60nMAssay Description:Binding affinity to human ER-alpha ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50094708(CHEMBL3589347)
Affinity DataKi:  756nMAssay Description:Binding affinity to human ER-beta ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50094708(CHEMBL3589347)
Affinity DataIC50:  330nMAssay Description:Antagonist activity at ER-beta (unknown origin) transfected in HEK293T cells assessed as inhibition of transcriptional activity after 24 hrs by lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50094708(CHEMBL3589347)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human recombinant HDAC6 after 15 mins by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50094708(CHEMBL3589347)
Affinity DataIC50:  534nMAssay Description:Inhibition of human recombinant HDAC1 after 15 mins by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50094708(CHEMBL3589347)
Affinity DataIC50:  1.08E+4nMAssay Description:Antagonist activity at ER-alpha (unknown origin) transfected in HEK293T cells assessed as inhibition of transcriptional activity after 24 hrs by luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed