BDBM50094751 3-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-8-(1H-indol-2-ylmethyl)-3,8-diaza-bicyclo[3.2.1]octane oxalate::3-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-8-(1H-indol-2-ylmethyl)-3,8-diazabicyclo[3.2.1]octane::CHEMBL341626

SMILES Fc1ccc(cc1)C(OCCN1CC2CCC(C1)N2Cc1cc2ccccc2[nH]1)c1ccc(F)cc1

InChI Key InChIKey=POOIGJPESWBTGB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50094751   

TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50094751(3-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-8-(1H-...)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity for rat Dopamine transporter.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50094751(3-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-8-(1H-...)
Affinity DataIC50: 104nMAssay Description:Binding affinity for rat 5-hydroxytryptamine transporter.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50094751(3-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-8-(1H-...)
Affinity DataIC50: 645nMAssay Description:Inhibition of [3H]5-HT reuptake in whole rat brain (minus cerebellum) homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50094751(3-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-8-(1H-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of [3H]DA reuptake in rat caudate homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50094751(3-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-8-(1H-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of [3H]dopamine uptake at DAT in Sprague-Dawley rat striatum synaptosomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed