BDBM50094987 5-Hydroxy Rofecoxib::5-Hydroxy-4-(4-methanesulfonyl-phenyl)-3-phenyl-5H-furan-2-one::CHEMBL1084

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1O)c1ccccc1

InChI Key InChIKey=NCBVUSNBLYMFPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094987   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094987(5-Hydroxy Rofecoxib | 5-Hydroxy-4-(4-methanesulfon...)
Affinity DataIC50:  8.70E+3nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094987(5-Hydroxy Rofecoxib | 5-Hydroxy-4-(4-methanesulfon...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed