BDBM50098214 2-[2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrrolidin-1-ylmethyl-1H-indol-6-yl]-ureido}-3-(3,4-difluoro-phenyl)-propionylamino]-5-guanidino-pentanoic acid (pyridin-4-ylmethyl)-amide::CHEMBL267059

SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccc(F)c(F)c1)NC(=O)Nc1ccc2c(CN3CCCC3)cn(Cc3c(Cl)cccc3Cl)c2c1)C(=O)NCc1ccncc1

InChI Key InChIKey=BSXVZSCKFMFANJ-BCRBLDSWSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098214   

TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098214(2-[2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrrolidin-1-yl...)
Affinity DataKd:  0.0400nMAssay Description:Binding affinity against Protease-activated receptor (PAR-1) using [3H]-s-(p-F-Phe)-homoarginine-L-homoarginine-KY-NH2, 10 nM (Kd= 15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098214(2-[2-{3-[1-(2,6-Dichloro-benzyl)-3-pyrrolidin-1-yl...)
Affinity DataIC50:  1.06E+3nMAssay Description:In vitro antagonist activity against Thrombin induced gel-filtered platelet (GFP) aggregation at 0.15 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed