BDBM50098599 CHEMBL3594310

SMILES CCS(=O)(=O)c1ccc2NC(=O)CCCc3ccc(cc3)[C@@H](Nc3ccc4c(N)nccc4c3)C(=O)NCc1c2

InChI Key InChIKey=JODGCVISYXBBJZ-MUUNZHRXSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50098599   

TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50098599(CHEMBL3594310)
Affinity DataKi:  8nMAssay Description:Inhibition of human Tissue factor/factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50098599(CHEMBL3594310)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant TF/F7a complex using S2288 as substrate preincubated for 15 mins followed by protein addition measured for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098599(CHEMBL3594310)
Affinity DataKi:  100nMAssay Description:Inhibition of human tissue kallikrein 1 measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098599(CHEMBL3594310)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human APC measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098599(CHEMBL3594310)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of human F10a using S2222 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098599(CHEMBL3594310)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of human trypsin measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098599(CHEMBL3594310)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of human plasma kallikrein using S2302 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098599(CHEMBL3594310)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of human thrombin using S2238 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098599(CHEMBL3594310)
Affinity DataKi: >3.50E+4nMAssay Description:Inhibition of human F9a measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed