BDBM50098599 CHEMBL3594310
SMILES CCS(=O)(=O)c1ccc2NC(=O)CCCc3ccc(cc3)[C@@H](Nc3ccc4c(N)nccc4c3)C(=O)NCc1c2
InChI Key InChIKey=JODGCVISYXBBJZ-MUUNZHRXSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50098599
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of human Tissue factor/factor 7aMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant TF/F7a complex using S2288 as substrate preincubated for 15 mins followed by protein addition measured for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human tissue kallikrein 1 measured for 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of human APC measured for 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of human F10a using S2222 as substrate measured for 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of human trypsin measured for 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Inhibition of human plasma kallikrein using S2302 as substrate measured for 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 5.80E+3nMAssay Description:Inhibition of human thrombin using S2238 as substrate measured for 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: >3.50E+4nMAssay Description:Inhibition of human F9a measured for 30 minsMore data for this Ligand-Target Pair