BDBM50101254 CHEMBL301723::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(3,4,5-trimethoxy-phenyl)-1,3-dihydro-isoindol-2-yl]-acetic acid

SMILES CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1

InChI Key InChIKey=JBMMQCZBDFDLEC-KAYWLYCHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101254   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50101254(CHEMBL301723 | [(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-...)
Affinity DataIC50:  66nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed