BDBM50101492 (R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4*-hydroxy-2-(3-phenyl-propyl)-succinamide::CHEMBL75403::N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4*-hydroxy-2-(3-phenyl-propyl)-succinamide

SMILES ONC(=O)C[C@@H](CCCc1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)NCCc1ccccc1

InChI Key InChIKey=FMRZZWFHPADOAW-SXOMAYOGSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50101492   

Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101492((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of the Gelatinase-A enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101492((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  0.0620nMAssay Description:Inhibitory constant against matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101492((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  0.0620nMAssay Description:Inhibition of the gelatinase-A enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101492((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  8.30nMAssay Description:Inhibition of the Stromelysin enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101492((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  8.30nMAssay Description:Inhibitory constant against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101492((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  8.30nMAssay Description:Inhibition of the stromelysin enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101492((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  203nMAssay Description:Inhibitory constant against matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101492((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  203nMAssay Description:Inhibition of the Collagenase enzyme was determined from purified NSO cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101492((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  203nMAssay Description:Inhibition of the collagenase enzyme.More data for this Ligand-Target Pair
In DepthDetails Article