BDBM50101853 (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid::(13E,15S)-11alpha,15-dihydroxy-9-oxoprost-13-en-1-oic acid::11alpha,15alpha-dihydroxy-9-oxo-13-trans-prostenoic acid::ALPROSTADIL::CHEMBL495::PGE-1::PGE1::prostaglandin E1

SMILES CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O

InChI Key InChIKey=GMVPRGQOIOIIMI-UHFFFAOYSA-N

Data  20 KI  6 IC50  11 EC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101853   

TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50101853((13E,15S)-11alpha,15-dihydroxy-9-oxoprost-13-en-1-...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed