BDBM50102311 3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6,7-dimethyl-pyrazolo[1,5-a]pyrimidine::CHEMBL331921
SMILES Cc1cnc2c(c(nn2c1C)-c1ccc(cc1)S(C)(=O)=O)-c1ccc(F)cc1
InChI Key InChIKey=WHGZGEFGZXHTST-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50102311
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphomaMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of COX-2 in human 143982 cells using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human 143.98.2 cell derived COX2 assessed as reduction in PGE2 level using arachidonic acid as substrate pretreated for 15 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human U-937 cell derived COX1 assessed as reduction in PGE2 level using arachidonic acid as substrate pretreated for 15 mins followed b...More data for this Ligand-Target Pair