BDBM50102468 4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-methyl]-piperidine-1-carboxylic acid tert-butyl ester::CHEMBL82169

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC(C1CCN(CC1)C(=O)OC(C)(C)C)C(O)=O

InChI Key InChIKey=LFOGEPKUSWRLCL-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50102468   

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102468(4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-m...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102468(4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-m...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102468(4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-m...)
Affinity DataIC50: 56.4nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102468(4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-m...)
Affinity DataIC50: 5.40nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102468(4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-m...)
Affinity DataIC50: 1.42E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102468(4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-m...)
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102468(4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-m...)
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102468(4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-m...)
Affinity DataIC50: 0.708nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102468(4-[Carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-m...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed