BDBM50103164 2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-5-methyl-biphenyl-3-carboxylic acid hydroxyamide::CHEMBL68271

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cc(C)cc1-c1ccccc1)C(=O)NO

InChI Key InChIKey=MQDWBVIPJPRWIJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103164   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103164(2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103164(2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50:  133nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103164(2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50:  7nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103164(2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50:  103nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed