BDBM50103168 CHEMBL71686::N-Hydroxy-3,5-dimethyl-2-[methyl-(4-phenylsulfanyl-benzenesulfonyl)-amino]-benzamide

SMILES CN(c1c(C)cc(C)cc1C(=O)NO)S(=O)(=O)c1ccc(Sc2ccccc2)cc1

InChI Key InChIKey=RRSNDPJAXNKWJB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103168   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103168(CHEMBL71686 | N-Hydroxy-3,5-dimethyl-2-[methyl-(4-...)
Affinity DataIC50:  8nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103168(CHEMBL71686 | N-Hydroxy-3,5-dimethyl-2-[methyl-(4-...)
Affinity DataIC50:  1.31E+3nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103168(CHEMBL71686 | N-Hydroxy-3,5-dimethyl-2-[methyl-(4-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103168(CHEMBL71686 | N-Hydroxy-3,5-dimethyl-2-[methyl-(4-...)
Affinity DataIC50:  727nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed