BDBM50103176 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiophen-3-ylmethoxy)-biphenyl-4-sulfonyl]-amino}-benzamide::CHEMBL71436

SMILES CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccsc2)cc1

InChI Key InChIKey=MLRVULAXCZJAAN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103176   

TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103176(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiophen...)
Affinity DataIC50:  4.64E+3nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103176(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiophen...)
Affinity DataIC50:  56nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103176(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiophen...)
Affinity DataIC50:  142nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50103176(5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiophen...)
Affinity DataIC50:  232nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed