BDBM50104839 CHEMBL3597525

SMILES OC(=O)CCCc1cn(CC(O)=O)c2c(\C=C\c3ccc(OCCCCc4c(F)ccc(F)c4F)cc3)cccc12

InChI Key InChIKey=UKCJWCGWHOCIIK-JLHYYAGUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104839   

TargetCysteinyl leukotriene receptor 2(Human)
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50104839(CHEMBL3597525)
Affinity DataIC50:  2.10nMAssay Description:Antagonist activity at human CysLT2 expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Human)
Setsunan University

Curated by ChEMBL
LigandPNGBDBM50104839(CHEMBL3597525)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human CysLT1 expressed in CHOK1 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed