BDBM50106857 3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL14613

SMILES COC(=O)C1C2CCC(CC1c1ccc(I)cc1)N2

InChI Key InChIKey=IBOZZWGMZPMXBO-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50106857   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Alcohol And Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  0.0600nMAssay Description:Ability to displace [3H]- paroxetine from Serotonin transporter in rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Alcohol And Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  0.0620nMAssay Description:Binding affinity to serotonin transporter (SERT) in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Alcohol And Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  0.640nMAssay Description:Ability to displace [3H]- beta-CIT from Dopamine transporter in rat striatal homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Alcohol And Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  0.640nMAssay Description:Binding affinity to dopamine transporter (DAT) in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  0.690nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Alcohol And Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  1.90nMAssay Description:Ability to displace [3H]- nisoxetin from Norepinephrine transporter in rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Alcohol And Drug Abuse Research Center

Curated by ChEMBL
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to norepinephrine (NE) transporter in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  7.5nMAssay Description:In vitro binding affinity of the compound was determined against human norepinephrin transporter in human embryonic kidney cell line by using [3H]-ni...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed