BDBM50108771 2'-amino-3'-methoxyflavone::2-(2-Amino-3-methoxy-phenyl)-chromen-4-one::2-(2-Amino-3-methoxy-phenyl)-chromen-4-one(PD98059)::2-(2-amino-3-methoxyphenyl)-4H-chromen-4-one::CHEMBL35482::PD-98059

SMILES COc1cccc(c1N)-c1cc(=O)c2ccccc2o1

InChI Key InChIKey=QFWCYNPOPKQOKV-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50108771   

LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
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PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Mitogen activated protein kinase kinase 1 (MKK1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Photinus pyralis luciferase by PK-Light assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Photinus pyralis luciferase by Easy lite assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of Photinus pyralis luciferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed