BDBM50109437 1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea::1-(4-bromophenyl)-3-(8-ethyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea::CHEMBL165600

SMILES CCn1cc2c(n1)nc(NC(=O)Nc1ccc(Br)cc1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=GQNTYJRUQFVQDY-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50109437   

TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109437(1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyra...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109437(1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyra...)
Affinity DataKi:  0.370nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109437(1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyra...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109437(1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyra...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]-MRE3008-F20 from human Adenosine A3 receptor expressed in HEK cells; range 0.29-0.47More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109437(1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyra...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50109437(1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyra...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-SCH-58,261 from human Adenosine A2A receptor expressed in HEK-293 cells; range 30-54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50109437(1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyra...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50109437(1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyra...)
Affinity DataKi:  296nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A2B receptor expressed in HEK-293 cells; range 261-336More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))TBA
LigandPNGBDBM50109437(1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyra...)
Affinity DataKi:  372nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50109437(1-(4-Bromo-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyra...)
Affinity DataKi:  500nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A1 receptor expressed in CHO cells; range 389-640More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed