BDBM50109715 2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid amide::CHEMBL151128

SMILES CCc1cc(\C=C\S(N)(=O)=O)cc(c1)C(=O)c1ccccc1

InChI Key InChIKey=QLMJXRSFPIZIKN-CMDGGOBGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50109715   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50:  1.20E+4nMAssay Description:Tested in vitro for inhibition of cyclooxygenase-1 in human blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50:  1.80E+4nMAssay Description:In vitro inhibition of cyclooxygenase-1 by inhibition of TXB2 generation with 1 uM arachidonic acid in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of PGE-2 generation by LPS-stimulated monocytes isolated from human blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50109715(2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid a...)
Affinity DataIC50:  1.00E+5nMAssay Description:Tested in vitro for inhibition of cyclooxygenase-2 in human blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed