BDBM50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570
SMILES CCCN[C@H]1CCc2nc(N)sc2C1
InChI Key InChIKey=FASDKYOPVNHBLU-ZETCQYMHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50116766
Affinity DataKi: 0.870nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 long (high/low affinity is given as 9.0/1800)More data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human Dopamine receptor D3 (high/low affinity is given as 25/1600)More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 long (high/low affinity is given as 27/5400)More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 8.5/130)More data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Effective concentration required for agonistic activity against human D3 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 9.20nMAssay Description:Effective concentration required for agonistic activity against rat D2 long receptorMore data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]-pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Effective concentration required for agonistic activity against human D4.2 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Friedrich-Alexander University
Curated by ChEMBL
Friedrich-Alexander University
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 long (high/low affinity is given as 230/53000)More data for this Ligand-Target Pair