BDBM50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570
SMILES CCCN[C@H]1CCc2nc(N)sc2C1
InChI Key InChIKey=FASDKYOPVNHBLU-ZETCQYMHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50116766
Affinity DataKd: 1.60nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]-pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Neurological Disorders And Stroke
Curated by ChEMBL
National Institute Of Neurological Disorders And Stroke
Curated by ChEMBL
Affinity DataKd: 12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
National Institute Of Neurological Disorders And Stroke
Curated by ChEMBL
National Institute Of Neurological Disorders And Stroke
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing G-alphai2 an...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute Of Neurological Disorders And Stroke
Curated by ChEMBL
National Institute Of Neurological Disorders And Stroke
Curated by ChEMBL
Affinity DataKd: 0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 14...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute Of Neurological Disorders And Stroke
Curated by ChEMBL
National Institute Of Neurological Disorders And Stroke
Curated by ChEMBL
Affinity DataKd: 0.0149nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 long receptor stably expressed in HEK293T cells co-expressing luciferase and CEK at high concentr...More data for this Ligand-Target Pair
Affinity DataKd: 0.0258nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 140 min...More data for this Ligand-Target Pair
Affinity DataKd: 4.5nMAssay Description:Displacement of [3H] mepyramine from human histamine H1 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RGS4 incuba...More data for this Ligand-Target Pair