BDBM50117239 CHEMBL123462::[4-(5-Butyl-3H-[1,2,4]triazolo[5,1-i]purin-8-yl)-phenyl]-dimethyl-amine

SMILES CCCCc1nc2nc[nH]c2c2nc(nn12)-c1ccc(cc1)N(C)C

InChI Key InChIKey=KYKFWXJBEABAMM-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50117239   

TargetAdenosine receptor A3(Homo sapiens (Human))
Nutrition Research Institute

Curated by ChEMBL
LigandPNGBDBM50117239(CHEMBL123462 | [4-(5-Butyl-3H-[1,2,4]triazolo[5,1-...)
Affinity DataKi:  1.25nMAssay Description:Inhibition of [125I]-AB-MECA binding to human Adenosine A3 receptor expressed in HEK cells; Range 0.82-1.91More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Nutrition Research Institute

Curated by ChEMBL
LigandPNGBDBM50117239(CHEMBL123462 | [4-(5-Butyl-3H-[1,2,4]triazolo[5,1-...)
Affinity DataKi:  49nMAssay Description:Inhibition of [3H]-CGS-21,680 binding to human Adenosine A2a receptor expressed in HEK-293 cells at 10000 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Nutrition Research Institute

Curated by ChEMBL
LigandPNGBDBM50117239(CHEMBL123462 | [4-(5-Butyl-3H-[1,2,4]triazolo[5,1-...)
Affinity DataKi:  1.31E+3nMAssay Description:Inhibition of [3H]-DPCPX binding to human Adenosine A1 receptor expressed in CHO cells;Range 983-1730More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Nutrition Research Institute

Curated by ChEMBL
LigandPNGBDBM50117239(CHEMBL123462 | [4-(5-Butyl-3H-[1,2,4]triazolo[5,1-...)
Affinity DataKi:  6.66E+3nMAssay Description:Inhibition of [3H]-DPCPX binding to human Adenosine A2B receptor expressed in HEK cells; Range 3580-12400More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Nutrition Research Institute

Curated by ChEMBL
LigandPNGBDBM50117239(CHEMBL123462 | [4-(5-Butyl-3H-[1,2,4]triazolo[5,1-...)
Affinity DataIC50:  0.670nMAssay Description:Displacement of [125I]-AB-MECA binding to human Adenosine A3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed