BDBM50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid
SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O
InChI Key InChIKey=PGAVKCOVUIYSFO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 62 hits for monomerid = 50118213
Affinity DataEC50: 480nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitatio...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+3nMAssay Description:The compound was evaluated for antagonist activity against phospholipase C coupled recombinant rat P2Y purinoceptor 4 (P2Y4)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of human erythrocytesMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 2 (P2Y2)More data for this Ligand-Target Pair
Affinity DataEC50: 1.26E+3nMAssay Description:Agonist activity at mouse P2Y2 receptor expressed in NG108-15 hybrid cells assessed as increase in intracellular calcium release by fluorescence assa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.51E+3nMAssay Description:Antagonist activity at mouse P2Y2 receptor expressed in NG108-15 hybrid cells assessed as inhibition of 1 uM UTP-induced intracellular calcium releas...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+3nMAssay Description:Agonist activity at human cloned P2Y1 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at human cloned P2Y4 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 424nMAssay Description:Agonist activity at human cloned P2Y6 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+3nMAssay Description:Agonist activity at human cloned P2Y1 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at human cloned P2Y4 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 640nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitatio...More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:The compound was evaluated for antagonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 4 (P2Y4)More data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.60nMAssay Description:Agonist activity at wild type P2Y2 receptor (unknown origin) expressed in human 1321N1 astrocytoma cells assessed as increase in intracellular calciu...More data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at P2Y2 receptor (unknown origin) assessed as reduction in inositol phosphate accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.25E+3nMAssay Description:Agonist activity at P2Y2 receptor in NG108-15 cells (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Agonist activity at P2Y2 receptor in BEA cells (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as [3H]-inositol phosphate accumulation measured after 90 mins by anion ex...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at P2Y2 receptor in human CF/T43 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Agonist activity at P2Y2 receptor expressed in 1321N1 cells assessed as cytosolic calcium levelMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at human P2Y2 transfected in human 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 550nMAssay Description:Agonist activity at human P2Y4 transfected in human 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 59nMAssay Description:Agonist activity at N-terminal HA epitope-tagged wild type 4 human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellula...More data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Agonist activity at human P2Y2More data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Agonist activity at human P2Y4More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as stimulation of PLC-induced [3H]inositol phosphate production afte...More data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Agonist activity at human P2Y4More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
Affinity DataEC50: 88nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
Affinity DataEC50: 640nMAssay Description:Agonist activity at human P2Y purinoceptor 2 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofl...More data for this Ligand-Target Pair
Affinity DataEC50: 480nMAssay Description:Agonist activity at human P2Y purinoceptor 4 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofl...More data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at human GFP-tagged P2Y2 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: 900nMAssay Description:Agonist activity at human GFP-tagged P2Y4 receptor expressed in human 1321N1 cells assessed as intracellular calcium mobilization by fura2/AM-based f...More data for this Ligand-Target Pair
Affinity DataEC50: 781nMAssay Description:Agonist activity at N-terminal HA epitope-tagged wild type 1 human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellula...More data for this Ligand-Target Pair
Affinity DataEC50: 80.4nMAssay Description:Agonist activity at N-terminal HA epitope-tagged wild type 3 human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellula...More data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+3nMAssay Description:The compound was evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 6 (P2Y6)More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Activity against rat P2Y2-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 450nMAssay Description:Activity against human P2Y2-GFP expressed in A549 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayMore data for this Ligand-Target Pair