BDBM50122844 CHEMBL3622175

SMILES COCc1cnc(nc1)N1CCC(CC1)[C@H]1C[C@H]1COCc1ccc(cc1F)S(C)(=O)=O

InChI Key InChIKey=KMUOWVJTLAOVPK-PZJWPPBQSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50122844   

TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122844(CHEMBL3622175)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122844(CHEMBL3622175)
Affinity DataIC50: >3.00E+4nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122844(CHEMBL3622175)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at mouse GPR119 by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122844(CHEMBL3622175)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human ERG by by patchXpress methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122844(CHEMBL3622175)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed