BDBM50123992 3-Cyclopropylmethyl-6-ethyl-11-methyl-8-phenylamino-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::CHEMBL352965
SMILES CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(Nc3ccccc3)cc21
InChI Key InChIKey=YCJIZJTVBUVHIS-DQNHKJGCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50123992
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity towards Opioid receptor kappa 1 from guinea pig brain using [3H]U69,593 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity towards Opioid receptor mu 1 from guinea pig brain using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Binding affinity towards Opioid receptor delta 1 from guinea pig brain using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Incorporation of [35S]- GTPgammaS into CHO membranes expressing human Opioid receptor mu 1More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataEC50: 5.90nMAssay Description:Incorporation of [35S]GTP-gamma-S, into CHO membranes expressing human Opioid receptor kappa 1More data for this Ligand-Target Pair