BDBM50130448 CHEMBL431041::N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-acetamide

SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(C)=O)nc12

InChI Key InChIKey=VCYDEUCPMLCHGS-UHFFFAOYSA-N

Data  12 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50130448   

Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  5nMAssay Description:Binding affinity to 5-HT1F (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  5nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >240nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >240nMAssay Description:Binding affinity to 5-HT1D (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >240nMAssay Description:Binding affinity to 5-HT1B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >240nMAssay Description:Binding affinity to 5-HT1A (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >240nMAssay Description:Binding affinity to 5-HT2C (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >240nMAssay Description:Binding affinity to 5-HT5A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >240nMAssay Description:Binding affinity to 5-HT2B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  250nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  270nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1B recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  620nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130448(CHEMBL431041 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataEC50:  36nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-HT1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed