BDBM50131270 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide::4'-nitro-3'-trifluoromethylisobutyranilide::CHEMBL806::Eulexin::FLUTAMIDE::Niftolide::alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro-m-propionotoluidide::niftolid
SMILES CC(C)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O
InChI Key InChIKey=MKXKFYHWDHIYRV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50131270
Affinity DataKi: 600nMAssay Description:Inhibition of AADAC in human kidney microsomeMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Binding affinity against GST-hARLBD was measured in SC-3 cell by using [3H]-testosterone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of human recombinant CES2 assessed as compound hydrolysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:Displacement of [3H]testosterone from wild type human androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+4nMAssay Description:Inhibition of AADAC in human jejunum microsomeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at AR in human MDA-kb2 cells cotransfected with MMTV-luc assessed as decrease in DHT-induced luciferase activity by reporter gene...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+5nMAssay Description:Antagonist activity at human androgen receptor expressed in human CV1 cells assessed as inhibition of receptor-mediated transactivation by MMTV-lucif...More data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Inhibition of 1.0 nM [3H]mibolerone binding to human androgen receptor of PC3/AR cell lysateMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of BSEP in human hepatocytes assessed as reduction in biliary excretion of [3H]-taurocholate in cell lysates after 15 mins by liquid scint...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
Affinity DataIC50: 6.08E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Antagonist activity at human androgen receptor expressed in mouse NIH3T3 cells assessed as inhibition of DHT-induced transcriptional activation after...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Antagonist activity at wild type human recombinant androgen receptor assessed as inhibition of testosterone-induced growth of mouse androgen dependen...More data for this Ligand-Target Pair
Affinity DataIC50: 1.43E+5nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 7.87E+4nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Inhibition of [3H]-Mibolerone binding to human Androgen receptor of PC3/AR Cell LysateMore data for this Ligand-Target Pair