BDBM50132644 4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphenyl-propyl)-piperidin-4-ol::CHEMBL325536

SMILES OC1(CCN(CCC(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=WUTNCUOBFDCXMO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132644   

TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132644(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphe...)
Affinity DataKi:  4nMAssay Description:Antagonistic activity against opioid receptor mu1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132644(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphe...)
Affinity DataKi:  4nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132644(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphe...)
Affinity DataKi:  225nMAssay Description:Binding affinity for opioid receptor like 1 expressed in HEK-293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132644(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphe...)
Affinity DataKi:  225nMAssay Description:Antagonistic activity against orphan FQ receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed