BDBM50134378 (2S)-5-{[(Z)-amino(imino)methyl]amino}-2-(methylamino)pentanoic acid::(2S)-5-{[amino(imino)methyl]amino}-2-(methylamino)pentanoic acid::(S)-5-Guanidino-2-methylamino-pentanoic acid::(S)-5-guanidino-2-(methylamino)pentanoic acid::CHEMBL332148::N-Monomethyl-L-arginine::N~5~-(DIAMINOMETHYLENE)-N~2~-METHYLORNITHINE

SMILES [#6]-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O

InChI Key InChIKey=NTWVQPHTOUKMDI-YFKPBYRVSA-N

Data  5 IC50

PDB links: 6 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50134378   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134378((2S)-5-{[(Z)-amino(imino)methyl]amino}-2-(methylam...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibitory concentration against neuronal nitric acid synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134378((2S)-5-{[(Z)-amino(imino)methyl]amino}-2-(methylam...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory concentration against inducible nitric acid synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50134378((2S)-5-{[(Z)-amino(imino)methyl]amino}-2-(methylam...)
Affinity DataIC50:  650nMAssay Description:Inhibition of human eNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134378((2S)-5-{[(Z)-amino(imino)methyl]amino}-2-(methylam...)
Affinity DataIC50:  950nMAssay Description:Inhibition of human nNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134378((2S)-5-{[(Z)-amino(imino)methyl]amino}-2-(methylam...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human iNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed