BDBM50137676 4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-ylamino)-benzenesulfonamide::CHEMBL74846::N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 7::N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 8

SMILES CC1OC(Nc2ccc(cc2)S(N)(=O)=O)C(O)C(O)C1O

InChI Key InChIKey=UQSFUQLWOVFBKX-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50137676   

TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  3.40nM ΔG°:  -11.4kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  10nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  13nM ΔG°:  -10.6kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  14nM ΔG°:  -10.5kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  510nM ΔG°:  -8.43kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(4-(3,4,5-Trihydroxy-6-methyl-tetrahydro-pyran-2-yl...)
Affinity DataKi:  680nM ΔG°:  -8.27kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed