BDBM50138405 CHEMBL341421::[(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl]methyl tetrahydrogen triphosphate

SMILES C1[C@H](O[C@H](S1)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N2C=C(C(=NC2=O)N)F

InChI Key InChIKey=WIEOLFZNMKSGEX-UHFFFAOYSA-N

Data  1 Kd

PDB links: 9 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138405   

TargetDNA polymerase subunit gamma-1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138405BDBM50138405([(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-...)
Affinity DataKd:  6.30E+4nMAssay Description:Binding affinity to human DNA polymerase gamma assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)