BDBM50138821 CHEMBL3747548::US9617272, Compound 66::US9981973, Compound 66
SMILES OC(CC1c2ccccc2-c2cnnn12)C1CCCCC1
InChI Key InChIKey=HIWSAOOCFITISA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50138821
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as conversion of N-formylkynurenine to kynurenine incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells incubated for 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of TDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The IC50 values for each compound were determined by testing the activity of TDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal 6His-tagged human IDO using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair