BDBM50140797 (2S,3S,4R,5S)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-methylsulfanylmethyl-pyrrolidine-3,4-diol; hydrochloride::CHEMBL554896

SMILES CSC[C@H]1N[C@H]([C@H](O)[C@@H]1O)c1c[nH]c2c(N)ncnc12

InChI Key InChIKey=PLIGEAXYYNDCDB-RXDXJJGDSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50140797   

TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50140797((2S,3S,4R,5S)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidi...)
Affinity DataKi:  1nMAssay Description:Equilibrium dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50140797((2S,3S,4R,5S)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidi...)
Affinity DataKi:  26nMAssay Description:Initial dissociation constant towards human 5'-methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50140797((2S,3S,4R,5S)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidi...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory concentration against Methylthioadenosine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed