BDBM50142451 1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-acetyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-[3-Acetyl-5-(1-methyl-1H-tetrazol-5-yl)-phenyl]-3-{3-[(S)-3-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL295415

SMILES CC(=O)c1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C

InChI Key InChIKey=MRXDPGHAGCROAM-FQEVSTJZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142451   

TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142451(1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)...)
Affinity DataIC50:  2.60nMAssay Description:Inhibitory concentration against C-C chemokine receptor type 3 using human [125I]-eotaxin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50142451(1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)...)
Affinity DataIC50:  3.77E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142451(1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)...)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed