BDBM50143184 CHEMBL3759063

SMILES O=c1ccc2c(n[nH]c2[nH]1)-c1cnc(s1)-c1cccnc1

InChI Key InChIKey=JCIZDZAGSUATFA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143184   

TargetDNA gyrase subunit B(Staphylococcus aureus)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143184(CHEMBL3759063)
Affinity DataIC50:  5.00E+4nMAssay Description:Binding affinity to full length Staphylococcus aureus GyrB by STD-NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143184(CHEMBL3759063)
Affinity DataIC50:  270nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseB ATPase activity using linear pBR322 DNA substrate incubated for 30 mins by fluorescence polarization ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143184(CHEMBL3759063)
Affinity DataIC50:  265nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase activity using pBR322 DNA as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed