BDBM50143951 1-Allyloxy-3-{4-[(4-chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-propan-2-ol::CHEMBL59639

SMILES OC(COCC=C)CN1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1

InChI Key InChIKey=WPDCPSIIDKVKBZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143951   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50143951(1-Allyloxy-3-{4-[(4-chloro-phenyl)-phenyl-methyl]-...)
Affinity DataKi:  100nMAssay Description:Predictive competitive inhibition of cytochrome P450 2D6 was determined in silicoMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Arqule

Curated by ChEMBL
LigandPNGBDBM50143951(1-Allyloxy-3-{4-[(4-chloro-phenyl)-phenyl-methyl]-...)
Affinity DataIC50:  401nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed