BDBM50146167 Capmatinib::INC-280::INCB-28060::NVP-INC280::US10738052, Example 7::US11261191, Example 7::US9944645, 7

SMILES CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1

InChI Key InChIKey=LIOLIMKSCNQPLV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146167   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM50146167(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Affinity DataIC50: <500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In DepthDetails US Patent