BDBM50150835 4-[N''-(2-Amino-2-methyl-propyl)-N''''-cyclohexyl-guanidino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide::CHEMBL366042

SMILES CC(C)(N)CNC(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1

InChI Key InChIKey=VOAHDPCQCTZCKL-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150835   

TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150835(4-[N''-(2-Amino-2-methyl-propyl)-N''''-cyclohexyl-...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of [125I]-NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150835(4-[N''-(2-Amino-2-methyl-propyl)-N''''-cyclohexyl-...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity for human melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150835(4-[N''-(2-Amino-2-methyl-propyl)-N''''-cyclohexyl-...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity for human melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150835(4-[N''-(2-Amino-2-methyl-propyl)-N''''-cyclohexyl-...)
Affinity DataIC50:  530nMAssay Description:Inhibition of [125I]NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150835(4-[N''-(2-Amino-2-methyl-propyl)-N''''-cyclohexyl-...)
Affinity DataEC50:  2.90E+3nMAssay Description:Binding affinity for human melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed