BDBM50150837 4-[((S)-N-(R)-Cyclohexyl-2,5-dimethyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide::CHEMBL184432

SMILES C[C@H]1CN([C@H](C)CN1)C(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1

InChI Key InChIKey=LKFLMXAGXFBGSV-VQTJNVASSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150837   

TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150837(4-[((S)-N-(R)-Cyclohexyl-2,5-dimethyl-piperazine-1...)
Affinity DataKi:  5.90nMAssay Description:Inhibition of [125I]-NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150837(4-[((S)-N-(R)-Cyclohexyl-2,5-dimethyl-piperazine-1...)
Affinity DataKi:  360nMAssay Description:Binding affinity for human melanocortin 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150837(4-[((S)-N-(R)-Cyclohexyl-2,5-dimethyl-piperazine-1...)
Affinity DataKi:  840nMAssay Description:Binding affinity for human melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150837(4-[((S)-N-(R)-Cyclohexyl-2,5-dimethyl-piperazine-1...)
Affinity DataKi:  2.80E+3nMAssay Description:Binding affinity for human melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150837(4-[((S)-N-(R)-Cyclohexyl-2,5-dimethyl-piperazine-1...)
Affinity DataIC50:  380nMAssay Description:Inhibition of human Melanocortin 5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed