BDBM50154937 CHEMBL518800

SMILES CC[C@H](CO)Nc1nc(NCc2ccc(cc2)-c2ccccn2)c2ncn(C(C)C)c2n1

InChI Key InChIKey=HOCBJBNQIQQQGT-LJQANCHMSA-N

Data  10 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154937   

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM50154937(CHEMBL518800)Copy SMILESCopy InChI

Affinity DataIC50:  225nMAssay Description:Inhibition of CDK5 (unknown origin) using histone H1 as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
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TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM50154937(CHEMBL518800)Copy SMILESCopy InChI

Affinity DataIC50:  62nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in sf9 cells using histone H1 as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI