BDBM50155225 CHEMBL365855::N-(5-Cyclobutyl-thiazol-2-yl)-2-phenyl-acetamide::N-(5-cyclobutylthiazol-2-yl)-2-phenylacetamide

SMILES O=C(Cc1ccccc1)Nc1ncc(s1)C1CCC1

InChI Key InChIKey=YIAFFFACXVWBIZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155225   

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155225(CHEMBL365855 | N-(5-Cyclobutyl-thiazol-2-yl)-2-phe...)
Affinity DataIC50:  25nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155225(CHEMBL365855 | N-(5-Cyclobutyl-thiazol-2-yl)-2-phe...)
Affinity DataIC50:  64nMAssay Description:Inhibition of CDK5/p25 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155225(CHEMBL365855 | N-(5-Cyclobutyl-thiazol-2-yl)-2-phe...)
Affinity DataIC50:  74nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed