BDBM50155226 CHEMBL185498::N-(5-Ethyl-thiazol-2-yl)-2-phenyl-acetamide

SMILES CCc1cnc(NC(=O)Cc2ccccc2)s1

InChI Key InChIKey=VXUBVHRAMUWWBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155226   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155226(CHEMBL185498 | N-(5-Ethyl-thiazol-2-yl)-2-phenyl-a...)
Affinity DataIC50:  412nMAssay Description:Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155226(CHEMBL185498 | N-(5-Ethyl-thiazol-2-yl)-2-phenyl-a...)
Affinity DataIC50:  621nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed