BDBM50155234 1-(5-Isopropyl-thiazol-2-yl)-3-phenyl-urea::CHEMBL186510

SMILES CC(C)c1cnc(NC(=O)Nc2ccccc2)s1

InChI Key InChIKey=PKOGEJUUQGCYAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155234   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155234(1-(5-Isopropyl-thiazol-2-yl)-3-phenyl-urea | CHEMB...)
Affinity DataIC50:  265nMAssay Description:Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155234(1-(5-Isopropyl-thiazol-2-yl)-3-phenyl-urea | CHEMB...)
Affinity DataIC50:  102nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed