BDBM50156071 3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide::3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide::CHEMBL190270

SMILES O=C(Nc1cc(nn1-c1ccccc1)-c1ccccc1)c1cccc(c1)C#N

InChI Key InChIKey=BKUIZWILNWHFHD-UHFFFAOYSA-N

Data  2 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156071   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50156071(3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide...)
Affinity DataEC50:  27nMAssay Description:Positive allosteric modulation of human mGluR5 stably expressed in CHO cells assessed as Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed