BDBM50157198 2-{Cyclohexyl-[4-(3-trifluoromethyl-benzyloxy)-benzoyl]-amino}-thiazole-5-carboxylic acid::CHEMBL360033

SMILES OC(=O)c1cnc(s1)N(C1CCCCC1)C(=O)c1ccc(OCc2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=KVOPMRICDIBARO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157198   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Neogenesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50157198(2-{Cyclohexyl-[4-(3-trifluoromethyl-benzyloxy)-ben...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase nonstructural protein 5B of hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neogenesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50157198(2-{Cyclohexyl-[4-(3-trifluoromethyl-benzyloxy)-ben...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neogenesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50157198(2-{Cyclohexyl-[4-(3-trifluoromethyl-benzyloxy)-ben...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory concentration against Cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed