BDBM50158465 (4-hydroxy-3,5-diiodophenyl)(2-methylbenzofuran-3-yl)methanone::CHEMBL389052::US9725430, Compound 1d::US9962362, Compound 1d

SMILES Cc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1

InChI Key InChIKey=QLUUKNMPBTWGBB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50158465   

TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158465((4-hydroxy-3,5-diiodophenyl)(2-methylbenzofuran-3-...)
Affinity DataKi:  7.20E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEyes absent homolog 3(Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158465((4-hydroxy-3,5-diiodophenyl)(2-methylbenzofuran-3-...)
Affinity DataIC50:  8.30E+3nMAssay Description:The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEyes absent homolog 3(Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158465((4-hydroxy-3,5-diiodophenyl)(2-methylbenzofuran-3-...)
Affinity DataIC50:  8.30E+3nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In DepthDetails US Patent