BDBM50160434 (6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)(4-methoxyphenyl)methanone::AM-630::AM630::CHEMBL181633::[6-iodo-2-methyl-1-(2-morpholin-4-ylethyl)indol-3-yl]-(4-methoxyphenyl)methanone::{6-iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl}[4-(methyloxy)phenyl]methanone
SMILES COc1ccc(cc1)C(=O)c1c(C)n(CCN2CCOCC2)c2cc(I)ccc12
InChI Key InChIKey=JHOTYHDSLIUKCJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 25 hits for monomerid = 50160434
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Centre Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in HEK293 cell membranes measured after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inverse agonist activity at human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inverse agonist activity at CB2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 31.2nMAssay Description:Binding affinity for human cannabinoid receptor 2 was determined by using [3H]-CP-55,940 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 31.2nMAssay Description:Binding affinity to cannabinoid CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 31.2nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
Affinity DataKi: 35.8nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 91nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 expressed in CHO cells after 90 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 840nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 expressed in CHO cells after 90 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
Affinity DataKi: 5.15E+3nMAssay Description:Inverse agonist activity at human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.15E+3nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
Affinity DataKi: 5.15E+3nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes measured after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 5.15E+3nMAssay Description:Binding affinity to cannabinoid CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.25E+3nMAssay Description:Agonist activity at CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Antagonist activity at cannabinoid CB2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 3.15E+3nMAssay Description:Inverse agonist activity at recombinant human CB2R expressed in CHOK1 cells assessed as increase in NKH477-stimulated intracellular cAMP levels after...More data for this Ligand-Target Pair
Affinity DataEC50: 603nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Inverse agonist activity at C-terminally prolink-tagged mouse CB2 receptor expressed in CHOK1 cells harboring beta-galactosidase enzyme fused beta-ar...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Inverse agonist activity at mouse CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-mediated cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 167nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 76.6nMAssay Description:Agonist activity at human CB2 receptor expressed CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair