BDBM50161747 3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]-1,2,3,4-tetrahydro-carbazol-9-yl}-propionic acid::CHEMBL373118

SMILES CN([C@@H]1CCc2c(C1)c1ccccc1n2CCC(O)=O)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=XKWVLGMVINJGLP-MRXNPFEDSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50161747   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161747(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of [3H]PGD-2 binding to human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161747(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of [3H]-SQ-29,548 binding to human Thromboxane A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161747(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibition of [3H]-PGD-2 binding to human Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161747(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PGD2-induced inositol phosphate formation at human Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161747(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of beta-arrestin translocation at human Thromboxane A2 receptor in BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161747(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50:  15nMAssay Description:Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50161747(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50:  26nMAssay Description:Inhibition of PGD2-induced inositol phosphate formation at human chemoattractant receptor-homologous molecule expressed on TH2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed